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A total of 6322 clinical questions available

How often should maintenance B12 injections be given?

Associated tags: Nutrition & metabolic diseases, time factors, vitamin B12

Question DetailsView Comments (0)

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Question answered:04/06/08

The CKS guideline ‘Anaemia - B12 and folate deficiency’ [1] has a section on maintenance, this reports:

“Maintenance dose (where the vitamin B12 deficiency is NOT thought to be diet related): administer hydroxocobalamin 1 mg intramuscularly every 3 months for life (standard dose). Note: the manufacturers' licence is for every 2–3 months.

Maintenance dose (where vitamin B12 deficiency is thought to be diet related): advise people either to take oral cyanocobalamin tablets 50–150 micrograms daily between meals, or have a twice-yearly hydroxocobalamin 1 mg injection (the injection regimen may be preferred in the elderly who are more likely to have malabsorption).”

Reference

1) http://www.cks.library.nhs.uk/anaemia_b12_and_folate_deficiency

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