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Question answered:29/08/07 Warning! this question is over two years old.
We came across the term (or closely related terms) in the clinical literature. For instance a 1990 Japanese paper is titled “Clinical studies on mycosis especially deep-seated candidiasis in blood disorder patients” [1]. A 1995 paper in Mycoses [2] reports:
“The sera were obtained from patients with deep-seated (n = 56) and superficial (n = 193) candidosis.”
A final example is a 2007 article in the Journal of antimicrobial chemotherapy [3] which reports:
“In deep-seated invasive candidiasis, including peritonitis, abdominal abscesses, CDC and arthritis, caspofungin was effective and safe at regular doses and up to 100 mg daily.”
However, this was a term not frequently used and we are unsure of the relationship with invasive candidiasis. Using simply the term 'deep seated candida infection' we found no reference to an association with breast pain.
With regard to the use of oral diflucan in breast feeding mothers, we feel that you should seek expert advice. Fortunately, there is a specialist Drugs in Lactation service, run by UK Medicines Information. They are best placed to comment on the relative safety of interventions in breastfeeding and will no doubt be able to advise on the relative efficacy. They can be contacted via http://www.ukmicentral.nhs.uk/drugpreg/qrg.htm.
References
1) http://pmid.us/2243190
2) http://pmid.us/8909026
3) http://pmid.us/17526917
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