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In patients who have presented with a lethal berry aneurysm, would screening of all children of the index patient be recommended?

Associated tags: berry aneurysm, Cardiovascular disease, family history, screening

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Question answered:11/05/07 Warning! this question is over two years old.

In February 2005 the NLH Q & A Service answered a question on screening relatives of patients with Berry aneurysms.In this answer, we reported no guidelines or secondary publications on this topic had been issued. [1].

 

We have updated our literature search using the NLH Specialist Libraries for Screening, and Cardiovascular Diseases, and the TRIP and Medline databases but again found no guidance or studies on screening for Berry or intracranial aneurysms in the previous two years. Thus, we consider our original answer to be current and this can be read in full at:

 

NLH Q & A Service. What are the current thoughts on screening for Berry aneurysm? - I have a lady whose father has recently had one confirmed - she was advised in Germany to be screened in UK!!! There is a known family history link & link to PCO disease but I can't find clear guidance on screening. Posted February 2005.
(http://www.clinicalanswers.nhs.uk/index.cfm?question=210  )

 

Of interest also may be an answer to a question on the hereditary basis of subarachnoid haemorrhage which also discusses screening:

 

NLH Q & A Service. Does subarachnoid haemorrhage have a hereditary basis? Are there any investigations recommended in a first degree relative? Posted September 2006. (http://www.clinicalanswers.nhs.uk/index.cfm?question=3963)


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